On a remote former submarine refueling facility called Aquatica, a team of scientists are searching for a cure for Alzheimer's disease. Dr. Susan McAlester genetically engineers three Mako sharks, intending to increase their brain capacity so that they can harvest the tissue as a cure for Alzheimer's. Unfortunately, the increased brain capacity also makes the sharks smarter, faster, and more dangerous. Aquatica's financial backers are skeptical and nervous about the tests, and send a corporate executive to visit the facility.
|Thomas Jane||Carter Blake|
|Saffron Burrows||Dr. Susan McCallister|
|LL Cool J||Sherman 'Preacher' Dudley|
|Michael Rapaport||Tom "Scoggs" Scoggins|
|Samuel L. Jackson||Russell Franklin|
|Stellan Skarsgård||Jim Whitlock|
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