When Phil and Debbie Winslow relocate from their native Kansas to the sunny climes of Orange County, their big-hearted, havoc-wreaking Great Dane gets a taste of the dog's life, California-style.
Lee Pace | Phil Winslow | |
Judy Greer | Debbie Winslow | |
Owen Wilson | Marmaduke (voice) | |
Emma Stone | Mazie (voice) | |
George Lopez | Carlos (voice) | |
Caroline Sunshine | Barbara Winslow |
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