Actress Myrtle Gordon (Gena Rowlands) is a functioning alcoholic actress who is a few days from the opening night of her latest play, concerning a woman distraught about aging. One night a car kills one of Myrtle's fans who is chasing her limousine in an attempt to get the star's attention. Myrtle internalizes the accident and goes on a spiritual quest, but fails to finds the answers she is after. As opening night inches closer and closer, fragile Myrtle must find a way to make the show go on.